Anti-G3BP 兔多克隆抗体-RNA加工-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

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Anti-G3BP 兔多克隆抗体

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￥1900

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货号： K1346581-100

预测分子量： 52 kDa

观测分子量： 68 kDa

别名： G3BP, G3BP 1, G3BP1, HDH VIII

应用 | 种属

WB H

规格：

100 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	Ras GTP酶激活蛋白结合蛋白1
别名	G3BP, G3BP 1, G3BP1, HDH VIII
Uniprot ID	P97855
免疫原	KLH偶联的小鼠G3BP合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	52 kDa / 68 kDa

应用

WB 免疫印迹

物种:人

稀释比:1: 300-1: 600

阳性样品:

背景

ATP- and magnesium-dependent helicase that plays an essential role in innate immunity. Participates in the DNA-triggered cGAS/STING pathway by promoting the DNA binding and activation of CGAS. Enhances also DDX58-induced type I interferon production probably by helping DDX58 at sensing pathogenic RNA. In addition, plays an essential role in stress granule formation. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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