Anti-GAD1 兔多克隆抗体-神经递质-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

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Anti-GAD1 兔多克隆抗体

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￥1900

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货号： K135151-100

预测分子量： 67 kDa

观测分子量： 67 kDa

别名： Gad1, GAD1, CPSQ1, GAD, SCP, glutamate decarboxylase 1

应用 | 种属

WB M,R

规格：

100 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	谷氨酸脱羧酶1
别名	Gad1, GAD1, CPSQ1, GAD, SCP, glutamate decarboxylase 1
Uniprot ID	P48318
免疫原	KLH偶联的小鼠GAD1合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	67 kDa / 67 kDa

应用

WB 免疫印迹

物种:小鼠, 大鼠

稀释比:1: 500-1: 1000

阳性样品:

背景

Glutamate decarboxylase 1 (brain, 67kDa) (GAD67), also known as GAD1, is one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. This enzyme is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

图像