| 蛋白质全称 | 线粒体60kDa热休克蛋白 |
|---|---|
| 别名 | HSP60,HSP-60,HuCHA60,CPN60,60 KDa Chaperonin,P60 Lymphocyte Protein,Heat Shock Protein 60 |
| Uniprot ID | P63038 |
| 免疫原 | KLH偶联的小鼠HSP60合成肽 |
| 抗体亚型 | IgG |
| 纯化方式 | 亲和纯化 |
| 亚细胞定位 | 线粒体基质 |
| 预测分子量./观测分子量. | 60 kDa / 60 kDa |
Heat shock protein 60 (HSP60) is a mitochondrial chaperonin that is typically held responsible for the transportation and refolding of proteins from the cytoplasm into the mitochondrial matrix. In addition to its role as a heat shock protein, HSP60 functions as a chaperonin to assist in folding linear amino acid chains into their respective three-dimensional structure. Through the extensive study of groEL, HSP60’s bacterial homolog, HSP60 has been deemed essential in the synthesis and transportation of essential mitochondrial proteins from the cell's cytoplasm into the mitochondrial matrix.
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