Anti-CITED2 兔多克隆抗体-缺氧-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

热门搜索： CD3 Actin GFP

Anti-CITED2 兔多克隆抗体

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￥1900

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货号： K135589-100

预测分子量： 28 kDa

观测分子量： 28 kDa

别名： Cited2,CITED2,ASD8,MRG-1,MRG1,P35SRJ,VSD2,Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2,MSG-related protein 1, P35srj,Mrg1,Cited2,Msg2

应用 | 种属

WB R

规格：

100 μL

产品描述
应用
背景
储存条件
图像

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产品信息

蛋白质全称	CBP/p300 互作转录激活因子2
别名	Cited2,CITED2,ASD8,MRG-1,MRG1,P35SRJ,VSD2,Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2,MSG-related protein 1, P35srj,Mrg1,Cited2,Msg2
Uniprot ID	O35740
免疫原	KLH偶联的小鼠CITED2合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	28 kDa / 28 kDa

应用

WB 免疫印迹

物种:大鼠

稀释比:1:500-1:1000

阳性样品:心

背景

CITED2, also named as P35srj, is a cAMP-responsive element-binding protein (CBP)/p300-transactivator, with an ED(Glu/Asp)-rich C-terminal domain that acts as an important modulator in the development of the heart .It is proposed to be a negative regulator of HIF-1α through its competitive binding to the CH1 domain of CBP/p300, which mediated signaling and to a decrease in HIF-1-responsive genes such as VEGF. In addition, it is also a co-activator of the transcriptional activity of the TFAP2 isoform, which is an extensively expressed nuclear protein with functions in embryogenesis, inflammation, and stress responses.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

图像

WB检测CITED2蛋白(货号 K135589).
样品: 经RIPA裂解液(货号KSG2002)处理的蛋白质.
封闭: 3%脱脂牛奶(货号KSGC310001)溶于TBST溶液, 室温孵育1小时.
—抗: 1: 500稀释, 4℃ 孵育过夜.
二抗: HRP标记山羊抗兔IgG (H+L) (货号KB69909), 1: 5000稀释, 室温孵育1小时.