Anti-2B4 兔多克隆抗体-淋巴细胞标志物-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

热门搜索： CD3 Actin GFP

Anti-2B4 兔多克隆抗体

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￥1900

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货号： K1334281-100

预测分子量： 45 kDa

观测分子量： 60 kDa

别名： NK cell type I receptor protein 2B4,NKR2B4,Non-MHC restricted killing associated,SLAM family member 4,SLAMF4,Signaling lymphocytic activation molecule 4,CD244,2b4,Nmrk

应用 | 种属

WB H,M,R

规格：

100 μL

产品描述
应用
背景
储存条件
图像

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产品信息

蛋白质全称	自然杀伤细胞受体2B4
别名	NK cell type I receptor protein 2B4,NKR2B4,Non-MHC restricted killing associated,SLAM family member 4,SLAMF4,Signaling lymphocytic activation molecule 4,CD244,2b4,Nmrk
Uniprot ID	Q07763
免疫原	小鼠2B4重组蛋白
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	45 kDa / 60 kDa

应用

WB 免疫印迹

物种:人,小鼠,大鼠

稀释比:1:500-1:1000

阳性样品:肺

背景

CD244 (2B4, SLAMF4) is a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via CD244 is thought to modulate NK-cell cytolytic activity. CD244 interacts with SLAMF2, causing the activation of both SLAMF4- and SLAMF2-expressing cells. Patients with systemic lupus erythmatosus have lower than normal levels of SLAMF4 expressed on their NK cells and monocytes, suggesting that SLAMF4 may play a role in the pathology of this autoimmune disease.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

图像

WB检测2B4蛋白(货号 K1334281).
样品: 经RIPA裂解液(货号KSG2002)处理的蛋白质.
封闭: 3%脱脂牛奶(货号KSGC310001)溶于TBST溶液, 室温孵育1小时.
—抗: 1: 1000稀释, 4℃ 孵育过夜.
二抗: HRP标记山羊抗兔IgG (H+L) (货号KB69909), 1: 5000稀释, 室温孵育1小时.