Anti-MRGX 兔多克隆抗体-DNA损伤修复,转录因子-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

热门搜索： CD3 Actin GFP

Anti-MRGX 兔多克隆抗体

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￥1900

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货号： K1342546-100

预测分子量： 32 kDa

观测分子量： 30 kDa

别名： IAA0026,MORF related gene X protein,MORF4L2,MORFL2,mortality factor 4 like 2,MRGX,Protein MSL3 2

应用 | 种属

WB M

规格：

100 μL

产品描述
应用
背景
储存条件
图像

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产品信息

蛋白质全称	致死因子4样蛋白2
别名	IAA0026,MORF related gene X protein,MORF4L2,MORFL2,mortality factor 4 like 2,MRGX,Protein MSL3 2
Uniprot ID	Q9R0Q4
免疫原	小鼠MRGX重组蛋白
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	32 kDa / 30 kDa

应用

WB 免疫印迹

物种:小鼠

稀释比:1:3000-1:6000

阳性样品:肝

背景

Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also a component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

图像

WB检测MRGX蛋白(货号 K1342546).
样品: 经RIPA裂解液(货号KSG2002)处理的蛋白质.
封闭: 3%脱脂牛奶(货号KSGC310001)溶于TBST溶液, 室温孵育1小时.
—抗: 1: 3000稀释, 4℃ 孵育过夜.
二抗: HRP标记山羊抗兔IgG (H+L) (货号KB69909), 1: 5000稀释, 室温孵育1小时.