Anti-LIN7B 兔多克隆抗体-细胞连接,囊泡运输-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

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Anti-LIN7B 兔多克隆抗体

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￥1900

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货号： K1342900-100

预测分子量： 23 kDa

观测分子量： 23 kDa

别名： hLin7B,hVeli2,lin 7 homolog B (C. elegans),LIN 7B,LIN7B,MALS 2,MALS2,Mammalian lin seven protein 2

应用 | 种属

WB M,R

规格：

100 μL

产品描述
应用
背景
储存条件
图像

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产品信息

蛋白质全称	lin-7同源蛋白B
别名	hLin7B,hVeli2,lin 7 homolog B (C. elegans),LIN 7B,LIN7B,MALS 2,MALS2,Mammalian lin seven protein 2
Uniprot ID	O88951
免疫原	KLH偶联的小鼠LIN7B合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	23 kDa / 23 kDa

应用

WB 免疫印迹

物种:小鼠,大鼠

稀释比:1:2000-1:3000

阳性样品:肾

背景

Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules . This complex may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

图像

WB检测LIN7B蛋白(货号 K1342900).
样品: 经RIPA裂解液(货号KSG2002)处理的蛋白质.
封闭: 3%脱脂牛奶(货号KSGC310001)溶于TBST溶液, 室温孵育1小时.
—抗: 1: 2000稀释, 4℃ 孵育过夜.
二抗: HRP标记山羊抗兔IgG (H+L) (货号KB69909), 1: 5000稀释, 室温孵育1小时.