Anti-SIRT6 兔多克隆抗体-染色质修饰酶-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

热门搜索： CD3 Actin GFP

Anti-SIRT6 兔多克隆抗体

咨询

￥1900

加入对比

货号： K1346575-100

预测分子量： 37 kDa

观测分子量： 40 kDa

别名： SIR2 like protein 6,SIR2L6,SIRT6

应用 | 种属

WB H

规格：

100 μL

产品描述
应用
背景
储存条件
图像

在线预览下载说明书

产品信息

蛋白质全称	NAD依赖性蛋白脱乙酰酶sirtuin-6
别名	SIR2 like protein 6,SIR2L6,SIRT6
Uniprot ID	P59941
免疫原	KLH偶联的小鼠SIRT6合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	37 kDa / 40 kDa

应用

WB 免疫印迹

物种:人

稀释比:1:300-1:500

阳性样品:HeLa细胞

背景

NAD-dependent protein deacetylase involved in various processes including telomere maintenance and gene expression, and consequently has roles in genomic stability, cell senescence and apoptosis Has very weak deacetylase activity and can bind NAD(+) in the absence of acetylated substrate (By similarity). Has deacetylase activity towards histone H3K9Ac and H3K56Ac Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle (By similarity). May also be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance (By similarity). Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

图像

WB检测SIRT6蛋白(货号 K1346575).
样品: 经RIPA裂解液(货号KSG2002)处理的蛋白质.
封闭: 3%脱脂牛奶(货号KSGC310001)溶于TBST溶液, 室温孵育1小时.
—抗: 1: 300稀释, 4℃ 孵育过夜.
二抗: HRP标记山羊抗兔IgG (H+L) (货号KB69909), 1: 5000稀释, 室温孵育1小时.