Anti-beta Arrestin 1 兔多克隆抗体-G蛋白偶联受体-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

Anti-beta Arrestin 1 兔多克隆抗体

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￥1900

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货号： K1346593-100

预测分子量： 47 kDa

观测分子量： 51 kDa

别名： ARB1, ARR1, ARRB1, Arrestin beta 1, arrestin, beta 1, Beta arrestin 1, β-Arrestin-1

应用 | 种属

WB H,M,R

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
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产品信息

蛋白质全称	β-抑制蛋白1
别名	ARB1, ARR1, ARRB1, Arrestin beta 1, arrestin, beta 1, Beta arrestin 1, β-Arrestin-1
Uniprot ID	Q8BWG8
免疫原	KLH偶联的小鼠beta Arrestin 1合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	47 kDa / 51 kDa

应用

WB 免疫印迹

物种:人, 小鼠, 大鼠

稀释比:1: 300-1: 500

阳性样品:

背景

Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin-associated sorting proteins) and recruiting the GPRCs to the adapter protein 2 complex 2 (AP-2) in clathrin-coated pits (CCPs).

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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