Anti-Insulin degrading enzyme/IDE 兔多克隆抗体-糖代谢-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

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Anti-Insulin degrading enzyme/IDE 兔多克隆抗体

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￥1900

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货号： K1334161-100

预测分子量： 118 kDa

观测分子量： 120 kDa

别名： Insulin protease, Insulinase, Insulysin, Ide, FLJ35968, Abeta-degrading protease

应用 | 种属

WB H,M,R

规格：

100 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	胰岛素降解酶
别名	Insulin protease, Insulinase, Insulysin, Ide, FLJ35968, Abeta-degrading protease
Uniprot ID	Q9JHR7
免疫原	小鼠IDE重组蛋白
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	118 kDa / 120 kDa

应用

WB 免疫印迹

物种:人, 小鼠, 大鼠

稀释比:1: 500-1: 1000

阳性样品:

背景

IDE(Insulin-degrading enzyme) belongs to the peptidase M16 family. It is also known as insulysin and is a neutral metallopeptidase that Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.The reduction of IDE expression may be a risk factor for AD, and that IDE may interact with APOE status to affect beta-amyloid metabolism.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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