Anti-EXOSC10/RRP6 兔多克隆抗体-RNA加工-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

热门搜索： CD3 Actin GFP

Anti-EXOSC10/RRP6 兔多克隆抗体

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￥1900

加入对比

货号： K1346113-100

预测分子量： 101 kDa

观测分子量： 110 kDa

别名： Autoantigen PM/Scl 2, EXOSC10, exosome component 10, p2, p3, p4, PM Scl, PM/Scl 100, PMSCL, PMSCL2, RRP6, Rrp6p

应用 | 种属

WB H,M

规格：

100 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	外泌体组分10
别名	Autoantigen PM/Scl 2, EXOSC10, exosome component 10, p2, p3, p4, PM Scl, PM/Scl 100, PMSCL, PMSCL2, RRP6, Rrp6p
Uniprot ID	P56960
免疫原	小鼠EXOSC10/RRP6重组蛋白
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	101 kDa / 110 kDa

应用

WB 免疫印迹

物种:人, 小鼠

稀释比:1: 800-1: 1500

阳性样品:

背景

Putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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