| 蛋白质全称 | 核糖体蛋白S6激酶β-1 |
|---|---|
| 别名 | S6K-beta-1,p70 alpha,p70 ribosomal S6 kinase alpha,p70 S6 kinase alpha,p70 S6K 1,p70 S6K alpha,p70 S6KA,p70(S6K),p70(S6K) alpha,p70S6K,P70S6K1,PS6K,Ribosomal protein S6 kinase I,RPS6KB1,S6K,S6K1,STK14A |
| Uniprot ID | Q8BSK8 |
| 免疫原 | KLH偶联的小鼠p70 S6 Kinase合成肽 |
| 抗体亚型 | IgG |
| 纯化方式 | 亲和纯化 |
| 亚细胞定位 | 细胞质, 细胞核 |
RPS6KB1(Ribosomal protein S6 kinase beta-1) is also named as STK14A, p70 S6KA and belongs to the S6 kinase subfamily. RPS6KB1 is a major substrate of MTOR and acts as a crucial effector of MTOR signaling pathway. It plays a key role in cell growth and proliferation by regulating INS sensitivity, metabolism, protein synthesis, and cell cycle. RPS6KB1 may play an important role in the progression of HCC and could serve as a potential molecular target for HCC therapy . RPS6KB1 is a 70 kDa protein and has 5 isoforms with the calculated molecular mass of 51-59 kDa produced by alternative initiation.
400-6027-270