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Anti-CYP2C19 兔多克隆抗体
¥1900
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货号: K1344625-100
预测分子量: 56 kDa
观测分子量: 47 kDa
别名: CYPIIC19,Cytochrome P450-11A,Cytochrome P450-254C,Mephenytoin 4-hydroxylase,CYPIIC17
应用 | 种属
WB M,R
规格:
产品信息
蛋白质全称 细胞色素P450 2C19
别名 CYPIIC19,Cytochrome P450-11A,Cytochrome P450-254C,Mephenytoin 4-hydroxylase,CYPIIC17
Uniprot ID P33261
免疫原 KLH偶联的人CYP2C19合成肽
抗体亚型 IgG
纯化方式 亲和纯化
预测分子量./观测分子量. 56 kDa / 47 kDa
应用
WB 免疫印迹
物种:小鼠,大鼠
稀释比:1:800-1:1500
阳性样品:肝
背景
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes.
储存条件
储存条件:储存条件在:-20℃下储存一年, 避免反复冻融.
储存缓冲液:含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.
图像
WB检测CYP2C19蛋白(货号 K1344625).
样品: 经RIPA裂解液(货号KSG2002)处理的蛋白质.
封闭: 3%脱脂牛奶(货号KSGC310001)溶于TBST溶液, 室温孵育1小时.
—抗: 1: 800稀释, 4℃ 孵育过夜.
二抗: HRP标记山羊抗兔IgG (H+L) (货号KB69909), 1: 5000稀释, 室温孵育1小时.

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