Anti-GRX2 兔多克隆抗体-细胞器标志物,能量代谢-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

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Anti-GRX2 兔多克隆抗体

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￥1900

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货号： K1345273-100

预测分子量： 17 kDa

观测分子量： 18 kDa

别名： GLRX2,Glutaredoxin 2,Glutaredoxin 2,mitochondrial,GRX2

应用 | 种属

WB M,R

规格：

100 μL

产品描述
应用
背景
储存条件
图像

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产品信息

蛋白质全称	线粒体谷氧还蛋白2
别名	GLRX2,Glutaredoxin 2,Glutaredoxin 2,mitochondrial,GRX2
Uniprot ID	Q923X4
免疫原	KLH偶联的小鼠GLRX2合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	17 kDa / 18 kDa

应用

WB 免疫印迹

物种:小鼠,大鼠

稀释比:1:300-1:600

阳性样品:睾丸

背景

Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

图像

WB检测GRX2蛋白(货号 K1345273).
样品: 经RIPA裂解液(货号KSG2002)处理的蛋白质.
封闭: 3%脱脂牛奶(货号KSGC310001)溶于TBST溶液, 室温孵育1小时.
—抗: 1: 300稀释, 4℃ 孵育过夜.
二抗: HRP标记山羊抗兔IgG (H+L) (货号KB69909), 1: 5000稀释, 室温孵育1小时.