Anti-GRK2 兔多克隆抗体-激素及受体-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

热门搜索： CD3 Actin GFP

Anti-GRK2 兔多克隆抗体

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￥1900

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货号： K1346656-100

预测分子量： 80 kDa

观测分子量： 80 kDa

别名： Beta-ARK-1, G-protein-coupled receptor kinase 2, Grk2, Adrbk1

应用 | 种属

WB H

规格：

100 μL

产品描述
应用
背景
储存条件
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产品信息

蛋白质全称	G 蛋白偶联受体激酶2
别名	Beta-ARK-1, G-protein-coupled receptor kinase 2, Grk2, Adrbk1
Uniprot ID	Q99MK8
免疫原	KLH偶联的小鼠GRK2合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	80 kDa / 80 kDa

应用

WB 免疫印迹

物种:人

稀释比:1: 300-1: 400

阳性样品:

背景

Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them (By similarity). Key regulator of LPAR1 signaling (By similarity). Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor (By similarity). Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner (By similarity). Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity (By similarity). Inhibits relaxation of airway smooth muscle in response to blue light

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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