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Anti-IRF8 兔多克隆抗体
¥1900
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货号: K1340251-100
预测分子量: 48 kDa
观测分子量: 50 kDa
别名: H ICSBP, ICSBP, ICSBP1, IRF-8, IRF8, MYLS
应用 | 种属
WB H,M,R
规格:
产品信息
蛋白质全称 干扰素调节因子8
别名 H ICSBP, ICSBP, ICSBP1, IRF-8, IRF8, MYLS
Uniprot ID P23611
免疫原 小鼠IRF8重组蛋白
抗体亚型 IgG
纯化方式 亲和纯化
预测分子量./观测分子量. 48 kDa / 50 kDa
应用
WB 免疫印迹
物种:人, 小鼠, 大鼠
稀释比:1: 1000-1: 2000
阳性样品:
背景
IRF8 also named as ICSBP1, is a transcription factor of the IFN regulatory factor (IRF) family. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. IRF8 specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the IFN consensus sequence (ICS)). It plays a negative regulatory role in cells of the immune system. It is predominantly in lymphoid tissues.
储存条件
储存条件:储存条件在:-20℃下储存一年, 避免反复冻融.
储存缓冲液:含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.
图像
IRF8_d1000_WB

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