| 蛋白质全称 | 丝裂原活化蛋白激酶1 |
|---|---|
| 别名 | APK1, ERK, ERK-2, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk, p42-MAPK, mitogen-activated |
| Uniprot ID | P63085 |
| 免疫原 | KLH偶联的小鼠ERK2合成肽 |
| 抗体亚型 | IgG |
| 纯化方式 | 亲和纯化 |
| 预测分子量./观测分子量. | 41/43 kDa / 42/44 kDa |
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
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