Anti-Ancient ubiquitous protein 1 兔多克隆抗体-泛素化相关-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

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Anti-Ancient ubiquitous protein 1 兔多克隆抗体

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货号： K1343020-100

预测分子量： 46 kDa

观测分子量： 46 kDa

别名： ancient ubiquitous protein 1,AUP1

应用 | 种属

WB H,M,R

规格：

100 μL

产品描述
应用
背景
储存条件
图像

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产品信息

蛋白质全称	脂滴调控VLDL组装因子AUP1
别名	ancient ubiquitous protein 1,AUP1
Uniprot ID	P70295
免疫原	KLH偶联的小鼠AUP1合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	46 kDa / 46 kDa

应用

WB 免疫印迹

物种:人,小鼠,大鼠

稀释比:1:800-1:1500

阳性样品:胰腺

背景

Plays a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome (By similarity). Plays a role in lipid droplet formation (By similarity). Induces lipid droplet clustering (By similarity). Recruits ubiquitin-conjugating enzyme UBE2G2 to lipid droplets which facilitates its interaction with ubiquitin ligases AMFR/gp78 and RNF139/TRC8, leading to sterol-induced ubiquitination of HMGCR and its subsequent proteasomal degradation (By similarity). Also required for the degradation of INSIG1, SREBF1 and SREBF2 (By similarity). Plays a role in regulating assembly and secretion of very low density lipoprotein particles and stability of apolipoprotein APOB (By similarity).

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

图像

WB检测Ancient ubiquitous protein 1蛋白(货号 K1343020).
样品: 经RIPA裂解液(货号KSG2002)处理的蛋白质.
封闭: 3%脱脂牛奶(货号KSGC310001)溶于TBST溶液, 室温孵育1小时.
—抗: 1: 1000稀释, 4℃ 孵育过夜.
二抗: HRP标记山羊抗兔IgG (H+L) (货号KB69909), 1: 5000稀释, 室温孵育1小时.