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Anti-SLC7A5/LAT1 兔多克隆抗体
¥1900
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货号: K1344613-100
预测分子量: 56 kDa
观测分子量: 37 kDa
别名: 4F2 LC,4F2 light chain,4F2LC,CD98 light chain,CD98LC,D16S469E,E16,hLAT1,Integral membrane protein E16,CD98,TA1,LAT1
应用 | 种属
WB H,M,R
规格:
产品信息
蛋白质全称 大中性氨基酸转运小亚基1
别名 4F2 LC,4F2 light chain,4F2LC,CD98 light chain,CD98LC,D16S469E,E16,hLAT1,Integral membrane protein E16,CD98,TA1,LAT1
Uniprot ID Q9Z127
免疫原 KLH偶联的小鼠SLC7A5/LAT1合成肽
抗体亚型 IgG
纯化方式 亲和纯化
预测分子量./观测分子量. 56 kDa / 37 kDa
应用
WB 免疫印迹
物种:人,小鼠,大鼠
稀释比:1:1000-1:1500
阳性样品:肝
背景
The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan. Functions as an amino acid exchanger. May play a role in the transport of L-DOPA across the blood-brain barrier (Probable). May act as the major transporter of tyrosine in fibroblasts. May mediate blood-to-retina L-leucine transport across the inner blood-retinal barrier. Can mediate the transport of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane. When associated with LAPTM4B, the heterodimer formed by SLC3A2 and SLC7A5 is recruited to lysosomes to promote leucine uptake into these organelles, and thereby mediates mTORC1 activation.
储存条件
储存条件:储存条件在:-20℃下储存一年, 避免反复冻融.
储存缓冲液:含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.
图像
WB检测SLC7A5/LAT1蛋白(货号 K1344613).
样品: 经RIPA裂解液(货号KSG2002)处理的蛋白质.
封闭: 3%脱脂牛奶(货号KSGC310001)溶于TBST溶液, 室温孵育1小时.
—抗: 1: 1000稀释, 4℃ 孵育过夜.
二抗: HRP标记山羊抗兔IgG (H+L) (货号KB69909), 1: 5000稀释, 室温孵育1小时.

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