Anti-EPHA8 兔多克隆抗体-生长因子及受体-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

热门搜索： CD3 Actin GFP

Anti-EPHA8 兔多克隆抗体

咨询

￥1900

加入对比

货号： K1345987-100

预测分子量： 111 kDa

观测分子量： 110 kDa

别名： EEK,EK3,EPH and ELK related kinase,EPH like kinase 3,EPH receptor A8,EPHA8,Ephrin type A receptor 8,HEK3,KIAA1459

应用 | 种属

WB M,R

规格：

100 μL

产品描述
应用
背景
储存条件
图像

在线预览下载说明书

产品信息

蛋白质全称	Ephrin A型受体8
别名	EEK,EK3,EPH and ELK related kinase,EPH like kinase 3,EPH receptor A8,EPHA8,Ephrin type A receptor 8,HEK3,KIAA1459
Uniprot ID	O09127
免疫原	KLH偶联的小鼠EPHA8合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	111 kDa / 110 kDa

应用

WB 免疫印迹

物种:小鼠,大鼠

稀释比:1:800-1:1500

阳性样品:肾

背景

Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation. With EFNA5 may regulate integrin-mediated cell adhesion and migration on fibronectin substrate but also neurite outgrowth. During development of the nervous system also plays a role in axon guidance. Downstream effectors of the EPHA8 signaling pathway include FYN which promotes cell adhesion upon activation by EPHA8 and the MAP kinases in the stimulation of neurite outgrowth.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

图像

WB检测EPHA8蛋白(货号 K1345987).
样品: 经RIPA裂解液(货号KSG2002)处理的蛋白质.
封闭: 3%脱脂牛奶(货号KSGC310001)溶于TBST溶液, 室温孵育1小时.
—抗: 1: 1000稀释, 4℃ 孵育过夜.
二抗: HRP标记山羊抗兔IgG (H+L) (货号KB69909), 1: 5000稀释, 室温孵育1小时.