Anti-c-Kit 兔多克隆抗体-细胞连接,白细胞抗原-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

热门搜索： CD3 Actin GFP

Anti-c-Kit 兔多克隆抗体

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￥1900

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货号： K133219-1-100

预测分子量： 109 kDa

观测分子量： 120-140 kDa

别名： C Kit, CD117, c-Kit, KIT, PBT, Proto-oncogene c-Kit, SCFR, Tyrosine protein kinase Kit, Sl, C-Kit, SCFR, KIT proto-oncogene receptor tyrosine kinase

应用 | 种属

WB H,M,R

规格：

100 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	肥大/干细胞生长因子受体Kit
别名	C Kit, CD117, c-Kit, KIT, PBT, Proto-oncogene c-Kit, SCFR, Tyrosine protein kinase Kit, Sl, C-Kit, SCFR, KIT proto-oncogene receptor tyrosine kinase
Uniprot ID	P05532
免疫原	小鼠c-Kit重组蛋白
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	109 kDa / 120-140 kDa

应用

WB 免疫印迹

物种:人, 小鼠, 大鼠

稀释比:1: 400-1: 800

阳性样品:

背景

KIT, also named as SCFR, c-Kit and CD117, is a transmembrane tyrosine kinase encoded by the cKit proto oncogene. It is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). KIT acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand(SCF) binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, and activation. Phosphorylation at tyrosine 721 of KIT allows binding and activation of PI3 kinase.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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