Nck1,NCK1,NCK,NCKalpha,nck-1,NCK adaptor protein 1
Uniprot ID
Q99M51
免疫原
小鼠NCK1重组蛋白
抗体亚型
IgG
纯化方式
亲和纯化
预测分子量./观测分子量.
42 kDa /
50 kDa
应用
WB 免疫印迹
物种:人,小鼠,大鼠
稀释比:1:500-1:1000
阳性样品:脾
背景
Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2.