| 蛋白质全称 | 肽基脯氨酰基顺反异构酶B |
|---|---|
| 别名 | Cyclophilin B,CYP S1,CYPB,PPIase B,PPIB,Rotamase B,S cyclophilin,SCYLP |
| Uniprot ID | P24369 |
| 免疫原 | KLH偶联的小鼠Cyclophilin B合成肽 |
| 抗体亚型 | IgG |
| 纯化方式 | 亲和纯化 |
| 亚细胞定位 | 内质网 |
| 预测分子量./观测分子量. | 24 kDa / 18 kDa |
PPIB, also named as CYPB, SCYLP, PPIase B and CYP-S1, belongs to the cyclophilin-type PPIase family and PPIase B subfamily. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIB is secreted in biological fluids such as blood or milk and binds to a specific receptor present on the human lymphoblastic cell line Jurkat and on human peripheral blood lymphocytes. The full-length of PPIB has 216aa (24 kDa), and a 33aa-signal peptide could be removed in the matrue form (about 19 kDa).
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