Anti-RASD2 兔多克隆抗体-小G蛋白相关-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

热门搜索： CD3 Actin GFP

Anti-RASD2 兔多克隆抗体

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￥1900

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货号： K1341538-100

预测分子量： 30 kDa

观测分子量： 30 kDa

别名： Ras homolog enriched in striatum,Rasd2,RASD family member 2,TEM2,Tumor endothelial marker 2,Rhes

应用 | 种属

WB M,R

规格：

100 μL

产品描述
应用
背景
储存条件
图像

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产品信息

蛋白质全称	GTP酶Rhes
别名	Ras homolog enriched in striatum,Rasd2,RASD family member 2,TEM2,Tumor endothelial marker 2,Rhes
Uniprot ID	P63032
免疫原	KLH偶联的小鼠RASD2合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	30 kDa / 30 kDa

应用

WB 免疫印迹

物种:小鼠,大鼠

稀释比:1:500-1:1500

阳性样品:肾

背景

This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

图像

WB检测RASD2蛋白(货号 K1341538).
样品: 经RIPA裂解液(货号KSG2002)处理的蛋白质.
封闭: 3%脱脂牛奶(货号KSGC310001)溶于TBST溶液, 室温孵育1小时.
—抗: 1: 1000稀释, 4℃ 孵育过夜.
二抗: HRP标记山羊抗兔IgG (H+L) (货号KB69909), 1: 5000稀释, 室温孵育1小时.