Anti-HMBOX1 兔多克隆抗体-转录因子-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

热门搜索： CD3 Actin GFP

Anti-HMBOX1 兔多克隆抗体

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￥1900

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货号： K1345276-100

预测分子量： 47 kDa

观测分子量： 47 kDa

别名： HMBOX1,HNF1LA,homeobox containing 1,Homeobox containing protein 1,PBHNF

应用 | 种属

WB M,R

规格：

100 μL

产品描述
应用
背景
储存条件
图像

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产品信息

蛋白质全称	含同源盒蛋白1
别名	HMBOX1,HNF1LA,homeobox containing 1,Homeobox containing protein 1,PBHNF
Uniprot ID	Q8BJA3
免疫原	KLH偶联的小鼠HMBOX1合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	47 kDa / 47 kDa

应用

WB 免疫印迹

物种:小鼠,大鼠

稀释比:1:1000-1:2000

阳性样品:脑

背景

Binds directly to 5'-TTAGGG-3' repeats in telomeric DNA (By similarity). Associates with the telomerase complex at sites of active telomere processing and positively regulates telomere elongation (By similarity). Important for TERT binding to chromatin, indicating a role in recruitment of the telomerase complex to telomeres . Also plays a role in the alternative lengthening of telomeres (ALT) pathway in telomerase-negative cells where it promotes formation and/or maintenance of ALT-associated promyelocytic leukemia bodies (APBs) (By similarity). Enhances formation of telomere C-circles in ALT cells, suggesting a possible role in telomere recombination (By similarity). Might also be involved in the DNA damage response at telomeres (By similarity).

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

图像

WB检测HMBOX1蛋白(货号 K1345276).
样品: 经RIPA裂解液(货号KSG2002)处理的蛋白质.
封闭: 3%脱脂牛奶(货号KSGC310001)溶于TBST溶液, 室温孵育1小时.
—抗: 1: 1000稀释, 4℃ 孵育过夜.
二抗: HRP标记山羊抗兔IgG (H+L) (货号KB69909), 1: 5000稀释, 室温孵育1小时.