Anti-SUN1 兔多克隆抗体-细胞连接-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

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Anti-SUN1 兔多克隆抗体

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货号： K1345657-100

亚细胞定位：核内膜

别名： KIAA0810,Protein unc 84 homolog A,Sad1/unc 84 protein like 1,SUN1,unc 84 homolog A (C. elegans),UNC84A

应用 | 种属

IHC/IF M,R

规格：

100 μL

产品描述
应用
背景
储存条件
图像

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产品信息

蛋白质全称	含SUN结构域的蛋白1
别名	KIAA0810,Protein unc 84 homolog A,Sad1/unc 84 protein like 1,SUN1,unc 84 homolog A (C. elegans),UNC84A
Uniprot ID	O94901
免疫原	KLH偶联的人SUN1合成肽
抗体亚型	IgG
纯化方式	亲和纯化
亚细胞定位	核内膜

应用

IHC/IF 免疫组织化学/免疫荧光

物种:小鼠,大鼠

稀释比:1:700-1:2100

阳性样品:胎盘

背景

As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton . The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning . Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration . Involved in telomere attachment to nuclear envelope in the prophase of meiosis implicating a SUN1/2:KASH5 LINC complex in which SUN1 and SUN2 seem to act at least partial redundantly.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

图像

IHC检测SUN1蛋白(货号 K1345657).
样品: 小鼠胎盘, 4%多聚甲醛 (货号KSG1101) 固定12-24小时.
抗原修复: Tris-EDTA抗原修复液(pH 9.0) (KSG1203), 98℃, 20分钟.
—抗: 1: 1400稀释, 4℃ 孵育过夜.
二抗: S-vision免疫组化多聚二抗(山羊抗兔),即用型 (货号KB3906), 室温孵育20分钟.

IHC检测SUN1蛋白(货号 K1345657).
样品: 大鼠胎盘, 4%多聚甲醛 (货号KSG1101) 固定12-24小时.
抗原修复: Tris-EDTA抗原修复液(pH 9.0) (KSG1203), 98℃, 20分钟.
—抗: 1: 1400稀释, 4℃ 孵育过夜.
二抗: S-vision免疫组化多聚二抗(山羊抗兔),即用型 (货号KB3906), 室温孵育20分钟.