| 蛋白质全称 | 纽蛋白 |
|---|---|
| 别名 | Metavinculin,Vcl,CMD1W,CMH15,MVCL,MV,VINC |
| Uniprot ID | P18206 |
| 免疫原 | 人Vinculin重组蛋白 |
| 抗体亚型 | IgG1 |
| 克隆号 | SB394 |
| 纯化方式 | 亲和纯化 |
| 亚细胞定位 | 细胞膜, 细胞质, 细胞连接 |
| 预测分子量./观测分子量. | 124 kDa / 124 kDa |
Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament (F-actin)-binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It may also play important roles in cell morphology and locomotion.
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