| 蛋白质全称 | Thy-1膜糖蛋白 |
|---|---|
| 别名 | CDw90,Thy-1 antigen,CD90,THY1,FLJ33325,Thy 1 cell surface antigen,Thy-1 cell surface |
| Uniprot ID | P04216 |
| 免疫原 | KLH偶联的人CD90合成肽 |
| 抗体亚型 | IgG |
| 纯化方式 | 亲和纯化 |
| 亚细胞定位 | 细胞膜 |
| 预测分子量./观测分子量. | 18 kDa / 25-37 kDa |
Thy-1 or CD90 (Cluster of Differentiation 90) is a 25–37 kDa heavily N-glycosylated,glycophosphatidylinositol (GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain, originally discovered as a thymocyte antigen. Thy-1 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Structural study of Thy-1 lead to the foundation of theImmunoglobulin superfamily, of which it is the smallest member, and led to some of the initial biochemical description and characterization of a vertebrate GPI anchor and also the first demonstration of tissue specific differential glycosylation.
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